Elizabeth McNally MD PhD



Elizabeth McNally MD PhD
Section of Cardiology, Department of Medicine

Dr. McNally cares for patients with genetic forms of cardiomyopathy and cardiac complications of muscle disease and neurological disease. Cardiomypathy is the most serious complucation of Friedreichs ataxia. In her research she studies the genetics of heart and muscle disease. Her laboratory examines mechanisms by which genetic mutations lead to cardiomyopathy, arrhythmias and vascular spasm. Her laboratory studies the dystrophin glycoprotein complex, including the sarcoglycans, which help stabilize the plasma membrane of cardiac and skeletal muscle. The laboratory is also interested in proteins that play a role in membrane repair in skeletal and cardiac muscle and in proteins at the nuclear membrane and their role in cardiac and skeletal muscle function.